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Folkemødet på Bornholm

ctDNA Forskningscentret på Folkemødet på Bornholm 2023!

Dato: 15. juni 2023
Tidspunkt: kl. 17:00 - 17:45
Sted: NI - Kræftens Bekæmpelse på Folkemødet
Sprog: Dansk

Læs mere om oplægget her: Sådan kan en blodprøve afsløre kræftens hemmeligheder

Claus Lindbjerg Andersen og Lars Dyrskjøt Andersen holder et oplæg om ctDNA på Folkemødet 2023. Oplægget er en del af DCCC - Danish Comprehensive Cancer Center's populærvidenskabelige foredrag og skal foregå i Kræftens Bekæmpelses telte. 

Baggrund for oplægget:
Dit blod kan afsløre hemmeligheder om dig og din sundhed. En blodprøve kan for eksempel sladre om kræft. For har du kræft et sted i kroppen, vil du ofte have DNA fra kræftcellerne i blodet. Og det kræftDNA viser ikke bare, at du har kræft – det kan også fortælle noget om, hvordan netop din kræft opfører sig, og hvilken behandling, der virker bedst for dig. Potentialet er enormt. KræftDNA fra blodprøver kan revolutionere vores kræftbehandlinger og øge overlevelsen og livskvaliteten. Og det er ikke ren fremtids-snak. Teknologien bliver lige nu afprøvet på flere danske hospitaler. Men hvordan virker det, og hvor langt er forskningen? Mød professor Lars Dyrskjøt og professor Claus Lindbjerg Andersen fra 'Dansk Forskningscenter for Cirkulerende Tumor DNA Guidet Kræftbehandling' til et populærvidenskabeligt foredrag, hvor der stilles skarpt på, hvad teknologien kan gøre for den enkelte patient nu og i fremtiden.


Seminar Series: Pneumatic tube system

Online meeting: Multicenter study of pneumatic tube systems’ influence on cfDNA/ctDNA analyses

Date: 12 april 2023
Time: 2:00 pm - 3:00 pm
Place: Online at Microsoft Teams (link will follow in an e-mail after registration deadline)
Seminar leaders: National Infrastructure 1 (NI1)
                             Rikke Fredslund Andersen, Senior Researcher, Department of Clinical Immunology and Biochemistry, Sygehus Lillebælt, Vejle
                             Cecilie Mondrup Jacobsen, Master of Science in Engineering, Department of Clinical Immunology and Biochemistry, Sygehus Lillebælt, Vejle
                             Luisa Matos Do Canto Alvim, Molecular Biologist, PhD, Department of Clinical Immunology and Biochemistry, Sygehus Lillebælt, Vejle

Target population: Anyone in the ctDNA Center who is interested in the influence from the pneumatic tube system - and who is at a hospital with the system

Registration: Register here
OBS this seminar is an internal seminar for center members - working at a university or hospital in Denmark.

 


 

Background:

Pneumatic tube systems (PTSs) are used in most hospitals in Denmark and abroad for efficiently transporting samples. With the implementation of cell-free DNA and circulating tumor DNA (cfDNA/ctDNA) analyses in the hospitals’ routine, it is crucial to assess the influence of using PTS for whole blood transportation on cfDNA/ctDNA quality/quantity.

 

Purpose:

The aim of this seminar is to plan a multicenter study involving the three most common PTS systems in Denmark in order to elucidate the influence of PTS on cfDNA/ctDNA quality/quantity using digital droplet PCR.

 


 

The Seminar Series
The Seminar is a part of a new initiative by The Danish National Center for Circulating Tumor DNA Guided Cancer Treatment; Seminar Series. The Seminar Series is a range of different seminars and workshops about ctDNA guided cancer treatment. They are open for everyone in the ctDNA Center - so feel free to share it with others who are working with or interested in ctDNA in Denmark. The seminars will be held approximately every second month.

The Seminar Series is an element of the ctDNA Research Center’s aim to facilitate national collaboration regarding research on ctDNA guided cancer treatment.

Everyone in the center can contribute with a workshop in their field of expertise or suggest wishes for a theme for a seminar - contact Anne Lærke Lorentzen, This email address is being protected from spambots. You need JavaScript enabled to view it.

Seminar Series: Bio-and Genome Bank Denmark

Seminar: Bio-and Genome Bank Denmark

What is Bio-and Genome Bank Denmark, and how can you as a researcher use the material and data?

 

Date: 11 May 2023
Time: 03:00 pm - 04:30 pm (kl. 15:00 - ca. 16:30)
Place: Online (link will follow in an e-mail after registration deadline)
Seminar leader: Estrid Høgdall, Professor, Dr. Med., Ph.D., The Molecular Unit, Department of Pathology, Herlev Hospital - and Director of the Bio-and Genome Bank Denmark
Target audience: Everyone in the center interested in hearing about Bio-and Genome Bank Denmark (Regionernes Bio-og Genombank, RBGB)

Registration: Please register here (registration deadline is 10 May 2023)

About the seminar
At the seminar, Estrid will be speaking about the history, organization, and purpose of Bio-and Genome Bank Denmark.

Additionally, she will present data about the material that has already been collected, and explain how researchers can obtain information about previously collected samples. She will also provide guidance on how researchers and clinicians can use the infrastructure of Bio-and Genome Bank Denmark for prospective collection of biological material. There will also be examples of cooperation agreements. 

At the secretariat of the Bio-and Genome Bank Denmark providing guidance and assistance is at the primary focus - so every requests are welcome!

Find more information at Bio-and Genome Bank Denmark webpage: https://www.regioner.dk/rbgb

 


About Seminar Series:
The Seminar is a part of a new initiative by The Danish National Center for Circulating Tumor DNA Guided Cancer Treatment; Seminar Series. The Seminar Series is a range of different seminars and workshops about ctDNA guided cancer treatment. They are open for everyone in the ctDNA Center - so feel free to share it with others who are working with or interested in ctDNA in Denmark.
The seminars will be held approximately every second month.

The Seminar Series is an element of the ctDNA Research Center’s aim to facilitate national collaboration regarding research on ctDNA guided cancer treatment.

Everyone in the center can contribute with a workshop in their field of expertise or suggest wishes for a theme for a seminar - contact Anne Lærke Lorentzen, This email address is being protected from spambots. You need JavaScript enabled to view it.

Seminar Series: Reference material

Seminar: Deciding the final design of the DCCC ctDNA Research Center's ctDNA reference material

Date: 22 March 2023
Time: 03:00 pm - 05:00 pm (kl. 15:00 - ca. 17:00)
Place: Online at Zoom (link will follow in an e-mail after registration deadline)
Seminar leaders: Laura Elgaard Iisager Jensen, Research Assistant, Department of Molecular Medicine (MOMA) Aarhus University and Aarhus University Hospital
                             Mads Heilskov Rasmussen, Cand.Scient., Ph.D., Department of Molecular Medicine (MOMA) Aarhus University and Aarhus University Hospital

Target population: Anyone in the center interested in being involved in the design of the DCCC ctDNA center’s FINAL reference material set for ctDNA detection methods.

Registration: Please register here (registration deadline is the 20th of March 2023)
OBS this seminar is for center members - working at a university or hospital in Denmark.

 


 

Background:

Circulating tumor DNA (ctDNA) is becoming a valuable tool for non-invasive cancer detection and profiling. However, effective clinical integration of ctDNA analysis requires standardization, benchmarking, and quality control of ctDNA assays. In the ctDNA center’s National Infrastructure 2 (NI2), we aim to develop stable and unlimited reference material (RefMat) for the common ctDNA detection methods, NGS and ddPCR, using artificial, mutated spike-in ctDNA. The RefMat will be available for other ctDNA laboratories to use, with the aim of achieving common standards for ctDNA detection across facilities, and a standardized protocol for optimal generation of ctDNA RefMat, in general.

 

Purpose:

The purpose of the workshop is:

  • To plan the design of the DCCC ctDNA Center's ctDNA RefMat in relation to conduction of the planned QA ring trials and ctDNA method benchmarking experiments.
  • To create the most useful, widespread, and accommodating panel of standards for all center members to use.

 

Agenda:
  • Presentation of the RefMat protocol.
  • Presentation of the draft version of RefMat spike-in mutations.
  • Discussion of the RefMat design:
    • Do the included mutations cover the most important aspects related to ctDNA detection such as noise level and mutation type ?
    • Are the mutations relevant, e.g. have high recurrence indices, are potential drug targets, and are my favorite mutations included ?
    • What allele frequency distribution should be represented ?
  • Discussion of the potential use of the RefMat, specifically:
    • QA ring trials.
    • Method benchmarking.
    • Internal laboratory control.

 

Preparation:
  • Read the handed out preliminary RefMat design and consider possibly changes or improvements relating to your laboratory's preferences.
    This will be e-mailed to you before the seminar

 


The Seminar Series
The Seminar is a part of a new initiative by The Danish National Center for Circulating Tumor DNA Guided Cancer Treatment; Seminar Series. The Seminar Series is a range of different seminars and workshops about ctDNA guided cancer treatment. They are open for everyone in the ctDNA Center - so feel free to share it with others who are working with or interested in ctDNA in Denmark.
The seminars will be held approximately every second month.

The Seminar Series is an element of the ctDNA Research Center’s aim to facilitate national collaboration regarding research on ctDNA guided cancer treatment.

Everyone in the center can contribute with a workshop in their field of expertise or suggest wishes for a theme for a seminar - contact Anne Lærke Lorentzen, This email address is being protected from spambots. You need JavaScript enabled to view it.


Apply for funding

The round of applications is open!

 

The DCCC ctDNA Research Center work for more national collaboration, breaking down barriers, and start new trials on ctDNA guided cancer treatment. One way we do this is to provide funds for clinical projects and methological studies under the center. It is possible to apply for 500.000 DKK per project. The center have funding application deadline twice a year.

With the fundings we hope to strengthen the national knowledge sharing, make a faster implementation of research results in the clinical setting, and do more evidence-based research.

As the DCCC ctDNA Research Center is a national center with a special focus on creating clinical impact from research projects, there are some criteria that must be met, for the projects to receive funding.
The current call is to be found here: Apply for Funding